A Global Phase 3 Study of Orelabrutinib+BR Vs.BR in Pts with TN MCL

PHASE3RecruitingINTERVENTIONAL
Enrollment

476

Participants

Timeline

Start Date

May 29, 2024

Primary Completion Date

June 25, 2031

Study Completion Date

June 25, 2032

Conditions
Mantle Cell Lymphoma
Interventions
DRUG

Orelabrutinib

Eligible patients will receive Orelabrutinib orally as per the protocol,until disease progression or other reasons for treatment discontinuation,whichever comes first.

DRUG

Bendamustine Injection

Eligible patients will receive Bendamustine by injection as per the protocol

DRUG

Rituximab

Eligible patients will receive Rituximab by injection as per the protocol

DRUG

Orelabrutinib Placebo

Eligible patients will receive Orelabrutinib Placebo orally as per the protocol

Trial Locations (39)

Unknown

RECRUITING

Beijing Cancer Hospital, Beijing

RECRUITING

Peking University Third Hospital, Beijing

RECRUITING

The First Affiliated Hospital of Bengbu Medical University, Bengbu

NOT_YET_RECRUITING

First Hospital of Jilin University, Changchun

RECRUITING

Hunan Cancer Hospital, Changsha

NOT_YET_RECRUITING

The First People's Hospital of Changzhou, Changzhou

RECRUITING

Sichuan Provincial People's Hospital, Chengdu

NOT_YET_RECRUITING

West China Hospital of Sichuan University, Chengdu

RECRUITING

Chongqinq Cancer Hospital, Chongqing

NOT_YET_RECRUITING

The First Affiliated Hospital of Chongqing Medical University, Chongqing

NOT_YET_RECRUITING

The second Hospital of Dalian Medical University, Dalian

RECRUITING

Fujing Cancer Hospital, Fuzhou

NOT_YET_RECRUITING

Union Hospital Affiliated to Fujian Medical University, Fuzhou

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

NOT_YET_RECRUITING

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

RECRUITING

Zhejiang University Medical School affiliated to the first Hospital, Hangzhou

RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

NOT_YET_RECRUITING

Cancer Hospital of Shandong First Medical University, Jinan

NOT_YET_RECRUITING

Shandong Provincial Hospital, Jinan

RECRUITING

The First Affiliated Hospital of Ningbo University, Jinan

NOT_YET_RECRUITING

The First Affiliated Hospital of Henan University of Science & Technology, Luoyang

RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

NOT_YET_RECRUITING

Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing

NOT_YET_RECRUITING

Cancer Hospital Affiliated to Fudan University, Shanghai

RECRUITING

Huashan Hospital of Fudan University, Shanghai

NOT_YET_RECRUITING

Shengjing Hospital of China Medical University, Shenyang

RECRUITING

The First Affiliated Hospital of China Medical University, Shenyang

NOT_YET_RECRUITING

The Fourth Hospital of Hebei Medical University, Shijiazhuang

NOT_YET_RECRUITING

Shanxi Cancer Hospital, Taiyuan

RECRUITING

Tianjin Cancer Hospital, Tianjin

RECRUITING

The Tumor Hospital Affiliated to Xinjiang Medical University, Ürümqi

RECRUITING

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and, Wuhan

NOT_YET_RECRUITING

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and, Wuhan

NOT_YET_RECRUITING

The First Affiliated Hospital of the PLA Air Force Military Medical University (Xijing Hospital), Xi'an

NOT_YET_RECRUITING

The Second Affiliated Hospital Of Xi'an Jiaotong University, Xi'an

NOT_YET_RECRUITING

Yibin Second People's Hospital, Yibin

RECRUITING

Henan Cancer Hospital, Zhengzhou

NOT_YET_RECRUITING

Henan Provincial People's Hospital, Zhengzhou

Sponsors
All Listed Sponsors
lead

InnoCare Pharma Inc.

INDUSTRY

NCT06363994 - A Global Phase 3 Study of Orelabrutinib+BR Vs.BR in Pts with TN MCL | Biotech Hunter | Biotech Hunter