Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD)

PHASE2RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

August 1, 2024

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2026

Conditions
Cognitive Decline, MildAlzheimer Disease
Interventions
DRUG

Fasudil

A ROCK inhibitor approved for treating vasospasms following subarachnoidal bleeding in Japan and China. Dosage: Participants will undergo a 2-week titration period at 60 mg daily before escalating to a maintenance dose of 120 mg daily.

DRUG

Placebo

Placebo tablets that look identical to the fasudil tablets and will follow the same dosing schedule as participants receiving fasudil.

Trial Locations (6)

Unknown

NOT_YET_RECRUITING

University Hospital of North Norway, Tromsø

NOT_YET_RECRUITING

Akershus Hospital:, Oslo

NOT_YET_RECRUITING

Haugesund Hospital, Haugesund

RECRUITING

Stavanger University Hospital, Stavanger

NOT_YET_RECRUITING

St. Olavs Hospital:, Trondheim

ENROLLING_BY_INVITATION

Haraldsplass Deaconess Hospital, Bergen

All Listed Sponsors
collaborator

University of Exeter

OTHER

collaborator

Helse Fonna

OTHER

collaborator

St. Olavs Hospital

OTHER

collaborator

University Hospital, Akershus

OTHER

collaborator

Haraldsplass Deaconess Hospital

OTHER

lead

Helse Stavanger HF

OTHER_GOV