The Combined Effect of TENS and TaVNS on Pressure and Heat Pain Thresholds in Pain-Free Subjects

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

July 20, 2024

Study Completion Date

October 20, 2024

Conditions
Healthy Volunteers
Interventions
DEVICE

Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)

"Both concha will be swabbed with an alcohol wipe before applying a thin layer of conductive gel. An ear clip electrode will be placed in the concha of both ears.~A frequency of 25 Hz will be applied with a pulse duration of 200 µs. Every 5 minutes, the subject will be asked if the intensity can be increased, decreased or remain the same to maintain the same level of intensity. Participants will also receive active TENS, 100 Hz, 200 µsec on forearm."

DEVICE

Placebo Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)

For placebo TaVNS, the intensity will be increased to a sensory level and then decreased to 0 mA. Participants will also receive active TENS, 100 Hz, 200 µsec on forearm.

DEVICE

Transcutaneous Electrical Nerve Stimulation

TENS will be applied on subject's forearm at a strong but comfortable intensity

Trial Locations (1)

06117

University of Hartford, West Hartford

All Listed Sponsors
lead

University of Hartford

OTHER

NCT06361381 - The Combined Effect of TENS and TaVNS on Pressure and Heat Pain Thresholds in Pain-Free Subjects | Biotech Hunter | Biotech Hunter