6
Participants
Start Date
March 26, 2024
Primary Completion Date
March 27, 2024
Study Completion Date
March 27, 2024
Thrombin generation assay (EnzySystem HemA version A - whole blood)
Whole blood obtained by venipuncture is immediately tested with the EnzySystem HemA version A), before and 0, 30, 120 and 240 minutes after administration of FEIBA.
Thrombin generation assay (Ceveron s100 (Technoclone) - fresh plasma)
Whole blood is centrifuged to obtain plasma. The fresh plasma is tested using the Ceveron s100.
Additional coagulation tests
"Plasma samples are frozen for later coagulation testing. The following tests are performed:~Factor VIII activity von Willebrand Factor antigen levels von Willebrand Factor ristocetin activity levels Prothrombin Fragment 1+2 levels ADAMTS13 activity FVIII antigen levels Nijmegen Hemostasis Assay"
Institute of Hematology and Blood Transfusion, Warsaw
Lead Sponsor
Instytut Hematologii i Transfuzjologii, Warschau, Poland
UNKNOWN
Enzyre B.V.
INDUSTRY