Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

PHASE2RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

March 17, 2025

Primary Completion Date

March 31, 2027

Study Completion Date

September 30, 2027

Conditions
Spinal FusionNausea and Vomiting, PostoperativeAnesthesia
Interventions
DRUG

Aprepitant

Two doses of 40mg (2ml) Aprepitant. One to be given on the morning of surgery and the second on the morning of post-op day 1

DRUG

Placebo

Two doses of dextrose syrup (2ml). One to be given on the morning of surgery and the second on the morning of post-op day 1

Trial Locations (1)

B3K 6R8

RECRUITING

IWK Health Sciences Center, Halifax

Sponsors

Lead Sponsor

All Listed Sponsors
lead

IWK Health Centre

OTHER

NCT06357234 - Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery | Biotech Hunter | Biotech Hunter