Carboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile Cancer

Induction: three cycles of intravenous carboplatin AUC5 (max 750 mg) and paclitaxel 175 mg/m2, during cycle 1, 2 and 3 (day 1, 22, 43)

"Induction: two cycles of intravenous pembrolizumab 400 mg during cycle 1 and 3 (day 1 and 43)~Adjuvant: up to seven cycles of fixed-dose intravenous pembrolizumab 400 mg, on day 1 every 6 weeks within 3-9 weeks after surgery"

Resection of part or all of the penis with complete removal of suspect lymphnodes in the inguinal and/or pelvic area