NCT06353685View on ClinicalTrials.gov

De-Escalation Postoperative Radiotherapy for Oral Squamous Cell Carcinoma With pCR/MPR.

PHASE2RecruitingINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2028

Conditions
De-escalated Radiotherapy; Head and Neck Cancer
Interventions
RADIATION

Continuous, hyperfractionated, accelerated radiotherapy(CHART)

high-risk CTV area (CTV1), 45Gy in total, fraction dose of 1.5Gy, twice a day, bioequivalent dose (BED) of 51.75Gy; Low-risk CTV area(CTV2), 39Gy in total , fraction dose of 1.3Gy, twice a day, BED of 44.07Gy; A total of 30 radiotherapy fraction were performed 10 times a week for 3 weeks.

Trial Locations (1)

Unknown

RECRUITING

Sun Yat-sen Memorial hospital, Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER