pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression

NARecruitingINTERVENTIONAL
Enrollment

270

Participants

Timeline

Start Date

April 17, 2024

Primary Completion Date

December 30, 2024

Study Completion Date

June 30, 2025

Conditions
Treatment Resistant DepressionMajor Depressive Disorder
Interventions
DEVICE

active rTMS treatment

Participants will receive 3 sessions per day of 1800 pulses per session, lasting for 21 days. Individualized targets will be generated using the pBFS method.

DEVICE

sham rTMS treatment

The parameters in the sham arms are the same as the active stimulation groups. Stimulation was delivered by the same device as the active group fitted with a sham coil.

Trial Locations (5)

Unknown

RECRUITING

Hebei Mental Health Center, Hebei

NOT_YET_RECRUITING

West China Hospital, Sichuan University, Chengdu

RECRUITING

Inner Mongolia Mental Health Center, Hohhot

NOT_YET_RECRUITING

Shandong Daizhuang Hospital, Jining

RECRUITING

The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang

Sponsors
All Listed Sponsors
lead

Changping Laboratory

OTHER

NCT06350396 - pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression | Biotech Hunter | Biotech Hunter