MA+AZA Regimen for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)

PHASE3RecruitingINTERVENTIONAL
Enrollment

154

Participants

Timeline

Start Date

January 18, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2028

Conditions
Acute Myeloid Leukaemia
Interventions
DRUG

mitoxantrone liposome, Ara-Cytarabine and azacitidine

Mitoxantrone hydrochloride liposome 24 mg/m2, IV every 4 weeks, day 1; Ara-Cytarabine 100 mg/m2, IV every 12 h, days 1-7; Azacitidine 100 mg, subcutaneous, once daily, days 1 to 7

DRUG

Daunorubicin,Ara-Cytarabine, azacitidine

Daunorubicin 60 mg/m2, intravenously, once daily, days 1 to 3; Ara-Cytarabine 100 mg/m2, IV drip, every 12h, days 1 to 7; Azacitidine 100 mg, subcutaneous, once daily, days 1 to 7;

Trial Locations (11)

214028

NOT_YET_RECRUITING

Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Wuxi

430071

RECRUITING

Zhongnan Hospital of Wuhan University, Wuhan

432100

NOT_YET_RECRUITING

The Central Hospital of Xiaogan, Xiaogan

434000

NOT_YET_RECRUITING

The First People's Hospital of Jingzhou, Jingzhou

434020

NOT_YET_RECRUITING

Jingzhou Central Hospital, Jingzhou

437100

NOT_YET_RECRUITING

Xianning Central Hospital, Xianning

438000

NOT_YET_RECRUITING

The Central Hospital of Huanggang, Huanggang

442000

NOT_YET_RECRUITING

Shiyan Taihe Hospital, Shiyan

443003

NOT_YET_RECRUITING

Yichang Central Hospital, Yichang

450052

NOT_YET_RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

030009

NOT_YET_RECRUITING

Shanxi Cancer Hospital, Taiyuan

All Listed Sponsors
collaborator

Ruijin Hospital

OTHER

collaborator

Shanxi Province Cancer Hospital

OTHER

collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Jingzhou Central Hospital

OTHER

collaborator

Yichang Central People's Hospital

OTHER

collaborator

Taihe Hospital

OTHER

collaborator

Central Hospital of Xiaogan

OTHER

collaborator

Xianning Central Hospital

OTHER

collaborator

The First People's Hospital of Jingzhou

OTHER

lead

Zhongnan Hospital

OTHER