Clinical Efficacy and Safety of Tender Point Infiltration (TPI) for Acute and Subacute Zoster Associated Pain

NAActive, not recruitingINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

October 1, 2026

Study Completion Date

December 1, 2027

Conditions
Herpes ZosterLocal InfiltrationAcute Pain
Interventions
DRUG

analgesic

Patients will receive daily 300 mg pregabalin in divided doses (150 mg/12 hours). Once the patient report mild pain (VAS ≤ 3), the trial for reducing the pregabalin dose will be done. Nonsteroidal anti-inflammatory drug celecoxib (200 mg on request, up to two times daily)27 and tramadol (100 mg on request, up to 400mg daily) will be available for as-needed analgesia.

BEHAVIORAL

Tender point infiltration

Lidocaine mixed with diprospan injected into tender points.

Trial Locations (1)

100070

Beijing Tiantan Hospital, Beijing

All Listed Sponsors
lead

Beijing Tiantan Hospital

OTHER