Intratumoral and Systemic Hiltonol® (Poly-ICLC) in Prostate Cancer Patients on Active Surveillance

PHASE2RecruitingINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

January 16, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Prostate Cancer Patients on Active Surveillance
Interventions
DRUG

Poly-ICLC intramuscular (IM) injection

1.5 mg IM (week 1), followed by paired 1.5 mg IM weekly from weeks 3-through10, and at weeks 14, 18, 22, 26, 30, 34, 38, 42 and 46 with a 4-week rest period between IM injections.

DRUG

Poly-ICLC, Intertumoral (IT) injection

1 mg IT once (week 2)

Trial Locations (1)

10029

RECRUITING

Icahn School of Medicine at Mount Sinai (ISMMS), New York

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Oncovir, Inc.

INDUSTRY

lead

Ashutosh Kumar Tewari

OTHER