AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

PHASE1RecruitingINTERVENTIONAL
Enrollment

148

Participants

Timeline

Start Date

March 29, 2024

Primary Completion Date

April 30, 2031

Study Completion Date

April 30, 2031

Conditions
Follicular LymphomaMantle Cell LymphomaHairy Cell LeukemiaLymphoplasmacytic LymphomaBurkitt LymphomaMarginal Zone LymphomaWaldenstrom MacroglobulinemiaLarge B-cell Lymphoma
Interventions
DRUG

CD22CART Infusion

Dosing and Administration Participants will be hospitalized to receive treatment with CD22CART, if not previously hospitalized, and will remain hospitalized for approximately 5 to 7 (±2) days. Patients may be discharged once all AEs have resolved to Grade 1 or better, or at the discretion of the treating physician. Participants may be discharged with non critical and clinically stable or slowly improving toxicities (e.g., renal insufficiency, cytopenias) even if \> Grade 1, if deemed appropriate by the investigator.

Trial Locations (1)

94304

RECRUITING

Stanford University, Palo Alto

All Listed Sponsors
collaborator

The Leukemia and Lymphoma Society

OTHER

lead

Stanford University

OTHER