NCT06337292View on ClinicalTrials.gov

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

PHASE3RecruitingINTERVENTIONAL
Enrollment

352

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

September 30, 2028

Study Completion Date

December 31, 2028

Conditions
Fracture of TibiaWound HealInfected WoundWound ComplicationWound Dehiscence
Interventions
DEVICE

Incisional Negative Pressure Wound Therapy (NPWT)

Participants in the treatment group will be standardized and will receive incisional NPWT using the any incisional VAC system that can apply 75-125mmHg continuous suction to the incision. The VAC sponge will be placed over the surgical wound at least 2cm in width and \>3cm in length.

Trial Locations (2)

21201

RECRUITING

University of Maryland R Adams Cowley Shock Trauma Center, Baltimore

03756

RECRUITING

Dartmouth-Hitchcock Medical Center, Lebanon

All Listed Sponsors
lead

Major Extremity Trauma Research Consortium

OTHER