Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

March 26, 2024

Primary Completion Date

May 26, 2024

Study Completion Date

November 26, 2024

Conditions
Malaria,FalciparumChemoprevention
Interventions
DRUG

Sulfadoxine/pyrimethamine plus amodiaquine

Seasonal Malaria Chemoprevention with SPAQ has not been trialed or introduced in Malawi yet. This intervention trial is different from others because of the location and because, traditionally, a full round of SMC with SPAQ that involves between 3-5 cycles is administered. Our trial is the first one that will only distribute one cycle of SMC with SPAQ. The data collected during the 42 days after SMC distribution will be used to estimate the medicines chemoprevention effectiveness at preventing malaria in children aged 3-59 months. This data, together with the resistance markers data will then be fed into a dynamical model that collaborators at Imperial College London have developed that will predic the potential impact of upscaling SMC in similar geographies.

All Listed Sponsors
lead

Malaria Consortium

OTHER

NCT06337253 - Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique | Biotech Hunter | Biotech Hunter