290
Participants
Start Date
June 28, 2024
Primary Completion Date
May 31, 2025
Study Completion Date
June 30, 2025
Tab. Trimethoprim-sulfamethoxazole, Tab. Clindamycin, Tab. Cephalexin, or Tab. Linezolid
"The choice of study drug will depend on the susceptibility of the respective isolate, expected drug interactions, contraindications, and expected side effects.~Investigators will assess whether the first-choice regimen can be given and then consider the alternative regimen. The antibiotics can be switched from first choice to the respective alternative medications during the intervention period if clinically necessary. The route of administration must be maintained according to the randomized group."
IV Cloxacillin, IV Cefazolin, IV Vancomycin, or IV Ceftaroline
"The choice of study drug will depend on the susceptibility of the respective isolate, expected drug interactions, contraindications, and expected side effects.~Investigators will assess whether the first-choice regimen can be given and then consider the alternative regimen. The antibiotics can be switched from first choice to the respective alternative medications during the intervention period if clinically necessary. The route of administration must be maintained according to the randomized group."
RECRUITING
Hospital Pulau Pinang, George Town
RECRUITING
Hospital Seberang Jaya, Seberang Jaya
RECRUITING
Hospital Raja Permaisuri Bainun, Ipoh
RECRUITING
Hospital Tengku Ampuan Rahimah, Klang
RECRUITING
Hospital Sultan Idris Shah Serdang, Kajang
RECRUITING
Hospital Ampang, Ampang
RECRUITING
Hospital Selayang, Selayang Baru Utara
RECRUITING
Hospital Tuanku Ja'afar, Seremban
RECRUITING
Hospital Melaka, Malacca
RECRUITING
Hospital Sultanah Aminah, Johor Bahru
RECRUITING
Hospital Sultanah Bahiyah, Alor Star
RECRUITING
Hospital Sultan Abdul Halim, Sungai Petani
Lead Sponsor
Clinical Research Centre, Malaysia
OTHER