NCT06334692View on ClinicalTrials.gov

Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

March 19, 2024

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2028

Conditions
Nephrotic Syndrome
Interventions
DIAGNOSTIC_TEST

"In-house ELISA, and ELISA kits from DBA Italy (Abbexa)."

"Nunc MaxiSorp ELISA plates will be coated with recombinant extracellular domain of human nephrin. Patient serum samples will be added in appropriate dilution. Plates will be then incubated with biotin-conjugated anti human IgG antibody followed by incubation with horseradish peroxidase (HRP)-avidin conjugate. Then tetramethylbenzidine substrate will be added, and absorbance read at 450 nm."

Trial Locations (1)

24020

RECRUITING

Clinical Research Center for Rare Disease Aldo e Cele Daccò, Ranica

All Listed Sponsors
lead

Mario Negri Institute for Pharmacological Research

OTHER