NCT06334198View on ClinicalTrials.gov

The Effect of Naldemedine on Opioid-induced Bowel Dysfunction

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 12, 2024

Primary Completion Date

March 31, 2025

Study Completion Date

March 31, 2025

Conditions
Opioid-Induced Bowel DysfunctionConstipation
Interventions
DRUG

Naldemedine

Naldemedine is administered orally once daily in the morning in a dosage of 0.2 mg.

DRUG

Placebo

Placebo is administered orally once daily in the morning.

DRUG

Tramadol

In both arms, tramadol is administered orally twice daily in a dosage of 100 mg (daily total of 200mg).

Trial Locations (1)

9000

RECRUITING

Aalborg University Hospital, Aalborg

All Listed Sponsors
lead

Asbjørn Mohr Drewes

OTHER