A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

March 20, 2024

Primary Completion Date

March 31, 2027

Study Completion Date

March 31, 2027

Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG

Durvalumab

10 mg/kg IV every 2 weeks or 1500 mg/kg IV every 4 weeks for up to 12 months.

DRUG

Sotorasib

960 mg, Patients who do not tolerate sotorasib at 960 mg can be dose reduced to 120 mg.

Trial Locations (11)

10065

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York

10604

Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison

11553

Memorial Sloan Kettering Nassau (All Protocol Activities), Uniondale

11725

Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities), Commack

18103

Lehigh Valley Health Network (Data Collection Only), Allentown

33136

University of Miami (Data Collection Only), Miami

37232

Vanderbilt University (Data Collection Only), Nashville

48109

University of Michigan (Data Collection Only), Ann Arbor

07920

Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge

07748

Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown

07645

Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

lead

Memorial Sloan Kettering Cancer Center

OTHER