Biomarker Modulation and the Inhibition of NKT1 Cells by Oral GRI-0621 in Patients With IPF

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

April 24, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

October 31, 2025

Conditions
Idiopathic Pulmonary FibrosisIPF
Interventions
DRUG

Tazarotene (GRI-0621)

Oral 4.5mg soft gel capsule

DRUG

Placebo

Oral 4.5mg soft gel capsule

Trial Locations (16)

2139

Concord General Repatriation Hospital, Concord

2217

St. George Hospital, Kogarah

2605

The Canberra Hospital, Garran

10467

Montefiore Medical Center, The Bronx

27103

Southeastern Research Center, Winston-Salem

29425

MUSC Pulmonary Research, Charleston

32224

Mayo Clinic, Jacksonville

92663

Newport Native MD, Inc., Newport Beach

EH16 4SA

Royal Infirmary Edinburgh, Edinburgh

B15 2GW

University Hospital Birmingham, Queen Elizabeth Hospital, Birmingham

CB2 0BB

Royal Papworth Hospital NHS Foundation Trust, Cambridge

EX2 5DW

Royal Devon and University Healthcare NHS Foundation Trust, Exeter

London

University College London Hospitals, London

BT47 6SB

Western Health and Social Care Trust (WHSCT), Londonderry

Norwich

Norfolk & Norwich University Hospital, Norwich

OX3 7LE

Oxford University Hospitals NHS Foundation Trust, Oxford

All Listed Sponsors
lead

GRI Bio Operations, Inc.

INDUSTRY

NCT06331624 - Biomarker Modulation and the Inhibition of NKT1 Cells by Oral GRI-0621 in Patients With IPF | Biotech Hunter | Biotech Hunter