Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease

NAEnrolling by invitationINTERVENTIONAL
Enrollment

320,000

Participants

Timeline

Start Date

May 14, 2025

Primary Completion Date

June 1, 2028

Study Completion Date

November 1, 2028

Conditions
Atrial FibrillationChronic Kidney DiseasesDiabetes Mellitus, Type 2
Interventions
OTHER

Intervention group

Subjects will be invited for a home-based screening (phase 1) that includes home-based testing; urine collection for detection of elevated albuminuria, and a heart rhythm measurement for detection of atrial fibrillation. Both home-based tests will be performed with CE-marked medical devices used according to their intended use. A subset of the population will also receive a short questionnaire. Depending on the results of the home-based tests, subjects might be invited for further screening in a diagnostic screening facility (phase 2), that includes collection of physical data, blood, and urine for the assessment of parameters that are indicative of cardiovascular disease, chronic kidney disease, diabetes type 2 or their risk factors. Participants will also receive a questionnaire. Based on the results of the diagnostic screening, participants may be referred to their GP for appropriate treatment according to the prevailing guidelines (phase 3)

Trial Locations (1)

Unknown

Stichting Amsterdam UMC, Amsterdam

All Listed Sponsors
collaborator

Dutch Cardiovascular Alliance

UNKNOWN

collaborator

University Medical Center Groningen

OTHER

collaborator

Dutch Heart Foundation

OTHER

collaborator

Dutch Kidney Foundation

OTHER

collaborator

Dutch Diabetes Research Foundation

OTHER

collaborator

Maastricht University

OTHER

collaborator

AstraZeneca

INDUSTRY

collaborator

UMC Utrecht

OTHER

collaborator

Radboud University Medical Center

OTHER

collaborator

Siemens Healthineers Nederland BV

UNKNOWN

collaborator

University of Twente

OTHER

collaborator

Roche Diagnostics Nederland BV

UNKNOWN

collaborator

Happitech BV

UNKNOWN

collaborator

Stichting Radboud Universiteit

UNKNOWN

collaborator

Stichting Netherlands Heart Institute

UNKNOWN

collaborator

Topicus.Healthcare BV

UNKNOWN

collaborator

Amsterdam UMC, location AMC

OTHER

lead

Prof. Dr. Folkert W. Asselbergs

OTHER