A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

March 19, 2024

Primary Completion Date

October 3, 2025

Study Completion Date

December 26, 2025

Conditions
Type 2 Diabetes
Interventions
DRUG

Cagrilintide

Participants will receive once-weekly cagrilintide subcutaneously.

DRUG

Semaglutide

Participants will receive once-weekly semaglutide subcutaneously.

DRUG

Placebo

Participants will receive placebo matched to cagrilintide and semaglutide subcutaneously.

Trial Locations (47)

1032

Szent Margit Rendelőintézet Nonprofit Kft., Budapest

1102

PVN Kutato Kft., Budapest

4025

Belinus Bt., Debrecen

4405

Borbánya Praxis E.Ü. Kft., Nyíregyháza

11000

CHC Zvezdara, Clinical department for endocrinology, Belgrade

11080

Clinical Hospital Center Bezanijska Kosa, Belgrade

Clinical Hospital Centre Zemun, Belgrade

11525

King Fahad Medical City, Riyadh

12372

King Khaled University Hospital,King Saud Univ. Med. City, Riyadh

12769

King Salman Bin Abdulaziz Hospital, Riyadh

14224

Southgate Medical Group, LLP, West Seneca

19000

Policlinic for diabetes, Zaječar

20132

IRCCS Ospedale San Raffaele Milano, Milan

21423

National Guard Hospital - Jeddah, Jeddah

23606

TPMG Clinical Research, Newport News

24127

Azienda Ospedaliera Papa Giovanni XXIII, Bergamo

32819

Headlands Research Orlando, Orlando

33024

Encore Medical Research LLC, Hollywood

33331

Encore Medical Research of Weston, Weston

36428

King Abdulaziz Hospital-Al Ahsa-National Guard, Al Ahsa

37660

Holston Medical Group, Kingsport

48098

Arcturus HC PLC Troy Med Res, Troy

67114

Alliance for Multispec Res, Newton

75230

Velocity Clinical Res-Dallas, Dallas

77479

Sugar Lakes Family Practice PA, Sugar Land

78231

Consano Clinical Research, LLC, Shavano Park

78233

Northeast Clinical Research of San Antonio, San Antonio

78526

Headlands Research Brownsville, Brownsville

78596

Valley Diab. & Endo Comp Ctr, Weslaco

88100

Policlinico Mater Domini Università di Catanzaro, Catanzaro

90255

Nat Res Inst Huntington Park, Huntington Park

91325

Valley Clinical Trials, Inc., Northridge

92701

Southern California Dermatology, Santa Ana

100853

Chinese People's Liberation Army General Hospital-Endocrinology, Beijing

210011

The Second Affiliated Hospital of Nanjing Medical University-Endocrinology, Nanjing

212001

The Affiliated Hospital of Jiangsu University-Endocrinology, Zhenjiang

250000

Jinan Central Hospital, Ji'Nan

Jinan Central Hospital Affiliated to Shandong University, Jinan

02115

Brigham & Women's Hospital, Boston

00161

Azienda Ospealiero Universitaria Policlinico Umberto I, Roma

35-055

Centrum Medyczne Medyk Sp. z o.o., Rzeszów

15-351

Osteo-Medic s.c. A. Racewicz, J. Supronik, Bialystok

15-797

Renew Clinic Sp. z o.o., Bialystok

90-338

Centrum Terapii Współczesnej J.M. Jasnorzewska S.K.A., Lodz

00-710

NBR Polska Tomasz Klodawski, Warsaw

02-507

Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji, Warsaw

22-400

Velocity Nova Sp. z o.o., Zamość

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY