NCT06319274View on ClinicalTrials.gov

Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure

PHASE2RecruitingINTERVENTIONAL
Enrollment

450

Participants

Timeline

Start Date

April 15, 2024

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
Acute Respiratory FailureEndothelial DysfunctionPulmonary Infection
Interventions
DRUG

Iloprost

Continuously infusion for 72 hours at 3 ml/hours. Treatment dose 1 ng/kg/min

DRUG

Isotonic saline

Continuously infusion for 72 hours at 3 ml/hours

Trial Locations (5)

2400

RECRUITING

Dept. of Anaesthesia and Intensive Care, Bispebjerg Hospital, Copenhagen

2650

RECRUITING

Dept. of Intensive care, Hvidovre Hospital, Hvidovre

2730

RECRUITING

Dept. of Intensive Care, Copenhagen University Hospital Herlev, Herlev

3400

RECRUITING

Dept. of Anaesthesia and Intensive Care, Nordsjaelands Hospital, Hillerød

4600

RECRUITING

Department of Anesthesia and Intensive Care Medicine, Zealand University Hospital, Køge

All Listed Sponsors
lead

Pär Johansson

OTHER