Surufatinib Combined With Toripalimab and HAIC in the Treatment of Inoperable or Metastatic Intrahepatic Cholangiocarcinoma

NANot yet recruitingINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

May 20, 2024

Primary Completion Date

May 20, 2024

Study Completion Date

May 20, 2027

Conditions
Intrahepatic Cholangiocarcinoma
Interventions
DRUG

Surufatinib、Toripalimab、Gemcitabine、Oxaliplatin

"The first week dose of Surufatinib was 150mg, the second week and the subsequent cycle was 200 mg once a day (QD) orally, Q3W, and the drug was suspended for one day on the day of HAIC; Toripalimab: 240mg intravenous infusion d1, Q3W;~HAIC: All patients received HAIC treatment on D1. Hepatic arterial perfusion therapy (HAIC) : a treatment cycle every 3 weeks for 4-6 consecutive cycles:~Surufatinib and Toripalimab were administered continuously until intolerable toxicity, disease progression, withdrawal of informed consent, loss of follow-up, and investigator judgment that medication should be discontinued (whichever occurred first)."

All Listed Sponsors
lead

Fudan University

OTHER

NCT06313554 - Surufatinib Combined With Toripalimab and HAIC in the Treatment of Inoperable or Metastatic Intrahepatic Cholangiocarcinoma | Biotech Hunter | Biotech Hunter