Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor

PHASE2RecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

February 28, 2028

Study Completion Date

February 28, 2029

Conditions
Thymic Epithelial TumorRadiotherapy Side EffectCarbon Ion RadiotherayHeavy Ion Radiotherapy
Interventions
RADIATION

Carbon ion radiotherapy

The patients will receive 72GyE per 18 fractions of carbon ion radiotherapy. Patients with thymus cancer should be combined with platinum-based regimen (including etoposide combined with cisplatin / carboplatin / loplatin / nedaplatin; paclitaxel combined with cisplatin or cisplatin / carboplatin / loplatin / nedaplatin; docetaxel combined with cisplatin / carboplatin / loplatin / nedaplatin) for at least 4 cycles. The primary endpoint was progression-free survival and toxicities, and the secondary endpoint was local relapse-free survival, overall survival and cause-specific survival.

OTHER

combined with platinum-based regimen

combined with platinum-based regimen

Trial Locations (1)

201513

RECRUITING

Shanghai Proton and Heavy Ion Center, Shanghai

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Jian Chen

OTHER