Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction

PHASE4RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 22, 2024

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2028

Conditions
Anterior Cruciate Ligament InjuriesPost-Traumatic Osteoarthritis of KneeBone Marrow Aspirate ConcentrateACL Injury
Interventions
BIOLOGICAL

Concentrated Bone Marrow Aspirate Injection

Intraoperatively, bone marrow will be harvested from the iliac crest with a commercial kit, it will then be prepared via centrifugation and an injection of the resulting concentrated product (cBMA) will be administered in the operative knee. cBMA is an autologous biologic product.

PROCEDURE

Sham Incision

A 2 mm sham incision will be made in the anatomical site where bone marrow would be harvested.

PROCEDURE

Revision Anterior Cruciate Ligament Reconstruction

This is the standard-of-care surgical procedure.

Trial Locations (2)

10021

RECRUITING

Hospital for Special Surgery, New York

30097

RECRUITING

Emory Orthopaedics & Spine Center, Atlanta

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Emory University

OTHER

collaborator

Arthritis Foundation

OTHER

lead

Hospital for Special Surgery, New York

OTHER