500
Participants
Start Date
March 18, 2025
Primary Completion Date
March 31, 2028
Study Completion Date
March 31, 2028
Biopsy Procedure
Undergo biopsy
Biospecimen Collection
Undergo collection of blood samples
Computed Tomography
Undergo CT
Echocardiography Test
Undergo ECHO
Electronic Health Record Review
Undergo review of SOC RNA testing results
Enfortumab Vedotin
Given IV
Immunohistochemistry Staining Method
Undergo IHC assay
Magnetic Resonance Imaging
Undergo MRI
Multigated Acquisition Scan
Undergo MUGA
Sacituzumab Govitecan
Given IV
Trastuzumab Deruxtecan
Given IV
RECRUITING
University of Virginia Cancer Center, Charlottesville
RECRUITING
VCU Massey Comprehensive Cancer Center, Richmond
RECRUITING
University of Florida Health Science Center - Gainesville, Gainesville
RECRUITING
Vanderbilt Breast Center at One Hundred Oaks, Nashville
RECRUITING
Vanderbilt University/Ingram Cancer Center, Nashville
RECRUITING
University of Kentucky/Markey Cancer Center, Lexington
RECRUITING
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
RECRUITING
University of Wisconsin Carbone Cancer Center - University Hospital, Madison
RECRUITING
Northwestern University, Chicago
RECRUITING
Washington University School of Medicine, St Louis
RECRUITING
Siteman Cancer Center-South County, St Louis
RECRUITING
Siteman Cancer Center at Christian Hospital, St Louis
RECRUITING
Siteman Cancer Center at West County Hospital, Creve Coeur
RECRUITING
Siteman Cancer Center at Saint Peters Hospital, City of Saint Peters
RECRUITING
Ochsner Medical Center Jefferson, New Orleans
RECRUITING
M D Anderson Cancer Center, Houston
RECRUITING
UC San Diego Health System - Encinitas, Encinitas
RECRUITING
UC San Diego Moores Cancer Center, La Jolla
RECRUITING
UC San Diego Medical Center - Hillcrest, San Diego
RECRUITING
Yale University, New Haven
RECRUITING
Smilow Cancer Hospital Care Center-Trumbull, Trumbull
RECRUITING
Dana-Farber Cancer Institute, Boston
National Cancer Institute (NCI)
NIH