Effect of Immunosuppressants With Adalimumab Biosimilars vs Corticosteroids on Noninfectious Uveitis

NAActive, not recruitingINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

March 27, 2024

Primary Completion Date

October 31, 2025

Study Completion Date

May 1, 2026

Conditions
Uveitis
Interventions
DRUG

Adalimumab Biosimilars Injection

Adalimumab biosimilars: 80 mg was subcutaneously injected for the first time in the first week, and then 40 mg was subcutaneously injected every two weeks from the first week to the 48 th week.

DRUG

Corticosteroid

Patients received no less than 1 mg / kg.d glucocorticoid at week 0, then implemented according to the standard reduction scheme.

DRUG

Immunosuppressive Agents

Mycophenolate mofetil 1g bid for more than 3 months, maintenance dose not less than 0.5g bid

Trial Locations (1)

518040

Shenzhen Eye Hospital, Shenzhen

All Listed Sponsors
collaborator

The Eye Hospital of Wenzhou Medical University

OTHER

collaborator

The First Affiliated Hospital of Soochow University

OTHER

collaborator

Shandong Eye Hospital

OTHER

collaborator

Shenzhen Eye Hospital

OTHER

lead

Zhongshan Ophthalmic Center, Sun Yat-sen University

OTHER

NCT06310837 - Effect of Immunosuppressants With Adalimumab Biosimilars vs Corticosteroids on Noninfectious Uveitis | Biotech Hunter | Biotech Hunter