Trial of Mirtazapine for Depression in IBD

PHASE2RecruitingINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

October 31, 2026

Conditions
Major Depressive DisorderInflammatory Bowel Diseases
Interventions
DRUG

Mirtazapine

30mg mirtazapine at night, escalated to 45mg after 4 weeks if \<20 percent improvement in depression from baseline. Total treatment duration 12 weeks.

DRUG

Placebo

1 placebo capsule at night, escalated to 2 capsules after 4 weeks if \<20 percent improvement in depression from baseline. Total treatment duration 12 weeks.

Trial Locations (4)

Unknown

RECRUITING

Guy's and St Thomas' Hospital NHS Foundation Trust, London

RECRUITING

Imperial College Healthcare NHS Trust, London

RECRUITING

King's College Hospital NHS Foundation Trust, London

RECRUITING

St Mark's Hospital, London

All Listed Sponsors
collaborator

King's College Hospital NHS Trust

OTHER

collaborator

Imperial College London

OTHER

collaborator

London North West Healthcare NHS Trust

OTHER

collaborator

Imperial College Healthcare NHS Trust

OTHER

collaborator

Guy's and St Thomas' NHS Foundation Trust

OTHER

lead

King's College London

OTHER

NCT06309472 - Trial of Mirtazapine for Depression in IBD | Biotech Hunter | Biotech Hunter