Observational Clinical Study of Letermovir for Preventing CMV Infection After Allo-HSCT

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

September 1, 2024

Study Completion Date

December 1, 2025

Conditions
Letemovir for the Prevention of CMV Infection After Allo-HSCT
Interventions
DRUG

Letermovir

Participants will be categorized into high-risk and intermediate-risk groups based on risk factors for CMV infection.Initiate letemovir prophylaxis on day +1 in high-risk patients and on days +7 to +14 in non-high-risk patients.(240 mg, qd in patients with concomitant cyclosporine; 480 mg, qd in patients with concomitant tacrolimus) to +100 days. For patients with comorbid GVHD who require intensive immunosuppression, consider extending the regimen to +200 days.

Trial Locations (1)

450000

RECRUITING

Cao, Weijie, Zhengzhou

All Listed Sponsors
lead

Cao Weijie

OTHER