A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis

NANot yet recruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

March 30, 2024

Primary Completion Date

July 30, 2026

Study Completion Date

December 30, 2026

Conditions
Decompensated Cirrhosis
Interventions
DRUG

HCL001 cell (homologous allogeneic hepatocytes) injection

The patient will undergo a DSA procedure in the hospital's operating room before infusion. A catheter will be inserted into the femoral artery and guided to the hepatic artery. Upon confirmation through imaging, HCL001 cell injection will be slowly infused through the catheter. During the infusion, the cells should be continuously agitated to prevent clumping. The infusion can be administered as a single dose or multiple doses, and after infusion, the patient will be closely monitored for at least one week.

All Listed Sponsors
lead

RenJi Hospital

OTHER

NCT06306781 - A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis | Biotech Hunter | Biotech Hunter