NCT06306638View on ClinicalTrials.gov

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

October 1, 2029

Study Completion Date

October 1, 2029

Conditions
Malignant Solid Neoplasm
Interventions
PROCEDURE

Biospecimen Collection

Undergo blood and tissue sample collection

PROCEDURE

Computed Tomography

Undergo CT

PROCEDURE

Endobronchial Ultrasound Bronchoscopy

Undergo EBUS

PROCEDURE

Interstitial Photodynamic Therapy

Undergo I-PDT

RADIATION

Palliative Radiation Therapy

Undergo palliative radiation therapy

OTHER

Physical Performance Testing

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

DRUG

Verteporfin

Given IV

DEVICE

Laser: ML7710-PDT

Delivering the therapeutic 689+/-3 nm laser light during I-PDT. Measuring light transmission.

Trial Locations (1)

14263

RECRUITING

Roswell Park Cancer Institute, Buffalo

Sponsors

Collaborators (1)

Modulight, Inc.
All Listed Sponsors
collaborator

Modulight, Inc.

UNKNOWN

collaborator

National Cancer Institute (NCI)

NIH

lead

Roswell Park Cancer Institute

OTHER