A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

April 3, 2024

Primary Completion Date

March 20, 2028

Study Completion Date

March 20, 2028

Conditions
MelanomaHead and Neck Squamous Cell CarcinomaPancreatic Ductal AdenocarcinomaColorectal CancerSolid Tumor
Interventions
DRUG

IPN01194

"IPN01194 will be taken orally over a period of 28 days (a Cycle) at the assigned dose level. The dose limiting toxicity (DLT) observation period consists of the first 28 days of treatment with IPN01194 (Cycle 1).~Participants will receive IPN01194 treatment beyond Cycle 1 until treatment is precluded by toxicity, disease progression, or upon participant's request or investigator decision."

DRUG

IPN01194

"All participants will receive IPN01194 orally for 28-day cycles at one of the two dose levels determined at the end of Phase I.~Participants will receive IPN01194 treatment until treatment is precluded by toxicity, disease progression, or upon participant's request or investigator decision"

Trial Locations (12)

22031

RECRUITING

Virginia Cancer Specialist, Fairfax

37203

RECRUITING

Sarah Cannon Research Institute (SCRI) - Nashville, Nashville

90025

RECRUITING

The Angeles Clinic and Research Institute - California, Los Angeles

92037

WITHDRAWN

UC San Diego Health System - La Jolla, San Diego

06510

RECRUITING

Yale Cancer Center - New Heaven, New Haven

Unknown

RECRUITING

Centre Léon Bérard - Lyon, Lyon

RECRUITING

Paris Saint-Louis, Paris

RECRUITING

Institut de Cancerologie de l'Ouest (St-Herblain), Saint-Herblain

RECRUITING

IGR-Villejuif, Villejuif

RECRUITING

Barcelona - Val D'Hebron, Barcelona

RECRUITING

Fundacion Jimenez Diaz - Madrid, Madrid

RECRUITING

M.D. Anderson Cancer Center Madrid, Madrid

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Ipsen

INDUSTRY