300
Participants
Start Date
February 1, 2024
Primary Completion Date
February 1, 2034
Study Completion Date
February 1, 2039
Endoscopic gastric suturing
Endoscopic suturing of the stomach to reduce volume and promote weight loss with either the Apollo Overstitch or Overstitch Sx system.
Endoscopic gastric plication
Endoscopic plication of the stomach to reduce volume and promote weight loss with either the POSE or Endomina system.
Revisional gastroplasty
Endoscopic suturing or plication of the stomach among patients who have previously undergone gastroplasty, sleeve gastrectomy, or Roux-en-Y gastric bypass to restrict the stomach and promote weight loss
Transoral outlet reduction endoscopy (TORe)
Reduction of the size of the gastro-jejunal anastomosis among patients who have previously undergone Roux-en-Y gastric bypass to promote weight loss. A variety of techniques may be used alone or in isolation including suturing (Apollo Overstitch), plication (POSE), argon photocoagulation, and endoscopic submucosal resection/dissection.
Duodenal mucosal resurfacing (DMR)
Endoscopic ablation of the post-ampullary duodenal mucosal to enhance improvement in glycaemic control among patients with type 2 diabetes.
Intragastric balloon(s)
The insertion of an intragastric implant into the stomach, which is subsequently filled with air or water to promote weight loss. Several intragastric balloons are available including Allurion, Heliosphere, Obalon, Orbera, and Spatz.
RECRUITING
Cleveland Clinic London, London
Cleveland Clinic London
OTHER