Platelet Rich Plasma Combined With Human Umbilical Cord Mesenchymal Stem Cells for Stage 3 and 4 Stress Injury

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 29, 2024

Primary Completion Date

November 25, 2024

Study Completion Date

November 25, 2024

Conditions
Pressure Injuries - Stage 3Pressure Injuries - Stage 4
Interventions
BIOLOGICAL

Platelet-rich plasma (PRP) combined with human umbilical cord mesenchymal stem cells (huMSCs)

Inject 3mL PRP+huMSCs (5 × 106) into the edge and bottom of the wound, with 0.5 ml at each point and a distance of approximately 1-3 cm between each point. Then, apply autologous PRP gel (PRP+thrombin mixture, 2ml) evenly on the wound, with a thickness of about 2mm

OTHER

Control group

Standard therapy for patients with stage 3 and 4 stress injury

Trial Locations (1)

252000

RECRUITING

Central laboratory, Liaocheng

All Listed Sponsors
lead

Liaocheng People's Hospital

OTHER