60
Participants
Start Date
March 1, 2024
Primary Completion Date
March 1, 2025
Study Completion Date
March 1, 2025
Chlorprocaine
we aim to examine whether selective nociceptive analgesia can be obtained in epidural analgesia for women in labor by using a combination of lidocaine (opens TPRV-1 and TPRA-1 channels) and chlorprocaine (polarized local anesthetic)
Lidocaine
Study participants will receive lidocaine alone
Lidocaine-chlorprocaine combination
study participants randomized to this study arm will receive a a 50:50 mixture of both drugs - where all drugs are administered in concentrations based on their ED50 doses, together with epidural opioids (fentanyl)
Hadassah Hebrew University Medical Center, POB 12000, Jerusalem
Hadassah Medical Organization
OTHER