A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

May 7, 2024

Primary Completion Date

October 31, 2025

Study Completion Date

April 30, 2026

Conditions
Chronic Graft Versus Host Disease
Interventions
DRUG

TQ05105 tablets

Rovadicitinib (TQ05105) is a novel, oral dual JAK 1/2 and Rho-associated kinases (ROCK) 1/2 inhibitor targeting inflammatory and fibrotic components of cGVHD.

Trial Locations (12)

200025

NOT_YET_RECRUITING

Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai

230001

NOT_YET_RECRUITING

Anhui Provincial Hospital, Hefei

300020

NOT_YET_RECRUITING

Hematology Hospital of the Chinese Academy of Medical Sciences, Tianjin

310000

RECRUITING

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

315040

NOT_YET_RECRUITING

The Affiliated People's Hospital of Ningbo University, Ningbo

441021

NOT_YET_RECRUITING

Xiangyang Central Hospital, Xiangyang

510180

NOT_YET_RECRUITING

Guangzhou First People's Hospital, Guangzhou

530021

NOT_YET_RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

710299

NOT_YET_RECRUITING

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an

730050

NOT_YET_RECRUITING

The 940th hospital of joint logistics support force of Chinese people's liberation army, Lanzhou

050000

NOT_YET_RECRUITING

The Second Hospital of Hebei Medical University, Shijiazhuang

Unknown

NOT_YET_RECRUITING

Tai'an Central Hospital, Taian

All Listed Sponsors
lead

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

INDUSTRY