A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

PHASE1RecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

August 15, 2024

Primary Completion Date

February 28, 2027

Study Completion Date

February 28, 2027

Conditions
Alzheimer Disease
Interventions
DRUG

LY3954068

Administered IT

DRUG

Placebo

Administered IT

DRUG

Flortaucipir F18

Administered intravenously (IV) prior to Positron Emission Tomography (PET) scan

Trial Locations (10)

27710

NOT_YET_RECRUITING

Duke University, Durham

30030

RECRUITING

CenExel iResearch, LLC (CenExel iRA), Decatur

32162

RECRUITING

Charter Research, LLC, The Villages

32751

RECRUITING

K2 Medical Research, LLC, Maitland

02129

NOT_YET_RECRUITING

Massachusetts General Hospital (MGH), Charlestown

08755

RECRUITING

CenExel AMRI, Toms River

113-8655

RECRUITING

The University of Tokyo Hospital, Bunkyō City

WC1N 3BG

NOT_YET_RECRUITING

National Hospital for Neurology and Neurosurgery (UCLH), London

S10 2JF

NOT_YET_RECRUITING

Royal Hallamshire Hospital, Sheffield

SO16 6YD

NOT_YET_RECRUITING

University Hospital Southampton, Southampton

All Listed Sponsors
lead

Eli Lilly and Company

INDUSTRY