A Phase II, Single-arm, Multicenter, Prospective Study of Cardunolizumab in Recurrent or Metastatic Vulvar and Vaginal Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 22, 2024

Primary Completion Date

March 22, 2026

Study Completion Date

March 22, 2027

Conditions
Vulvar and Vaginal Cancer
Interventions
DRUG

Cardunolizumab

"1. Not systematically treated:~ Cardunolizumab (10mg/kg) + Cisplatinum (50mg/m2)/ Carboplatinum (AUC 4-5) + Paclitaxel (175mg/m2) ± Bevacizumab (15mg/kg) for 6 cycles, every 3 weeks (Q3W), and then Cardunolizumab ± Bevacizumab Q3W maintenance treatment.~2. Previous systematic treatment:~Cardunolizumab (10mg/kg) + Chemotherapy regimen selected by the investigator ± Bevacizumab (15mg/kg) for 6 cycles, every 3 weeks (Q3W), and then Cardunolizumab ± Bevacizumab Q3W maintenance treatment."

Trial Locations (1)

310005

RECRUITING

Zhejiang Cancer Hospital, Hangzhou

Sponsors
All Listed Sponsors
collaborator

Akeso

INDUSTRY

collaborator

Innovent Biologics, Inc.

OTHER

lead

Zhejiang Cancer Hospital

OTHER

NCT06292689 - A Phase II, Single-arm, Multicenter, Prospective Study of Cardunolizumab in Recurrent or Metastatic Vulvar and Vaginal Cancer | Biotech Hunter | Biotech Hunter