85
Participants
Start Date
November 30, 2025
Primary Completion Date
June 30, 2029
Study Completion Date
June 30, 2032
Cyclophosphamide
Cyclophosphamide is given by intravenous (IV) infusion once every 3 weeks for 4 doses total (12 weeks). It will be given together with Epirubicin.
Epirubicin
Epirubicin is given by intravenous (IV) infusion once every 3 weeks for 4 doses total (12 weeks). It will be given together with Cyclophosphamide.
Docetaxel
Docetaxel is given by intravenous (IV) infusion once every 3 weeks for 4 doses total (12 weeks). It will be given together with Carboplatin. Dosing will start after treatment with Epirubicin and Cyclophosphamide (EC) is completed.
Carboplatin
Carboplatin is given by intravenous (IV) infusion once every 3 weeks for 4 doses total (12 weeks). It will be given together with Docetaxel. Dosing will start after treatment with EC is completed.
Breast Surgery
Participants will undergo breast surgery after completing dosing with Carboplatin and Docetaxel to remove any remaining cancer in the breast.
Capecitabine
Capecitabine is a pill that will be taken by mouth daily for 6 months after surgery is completed.
Lagos University Teaching Hospital, Yaba
Lagos State University Teaching Hospital, Ikeja
University of Ibadan Hospital, Ibadan
Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife
University of Chicago
OTHER