50
Participants
Start Date
June 5, 2024
Primary Completion Date
November 30, 2026
Study Completion Date
November 30, 2026
Tadalafil
Patients will be given either the intervention medication or a placebo (double-blinded, randomized trial) and will be asked to take the medication every day for 6 months in conjunction with weekly exercise sessions.
Placebo
Patients will be given either the intervention medication or a placebo (double-blinded, randomized trial) and will be asked to take the medication every day for 6 months in conjunction with weekly exercise sessions.
Exercise Training
The home-based cycling exercise training program is designed to improve muscle strength and endurance. Participants will engage in individualized exercise sessions up to four times per week, lasting up to 40 minutes each. Live video and heart rate monitoring will ensure proper exercise performance and allow for adjustments to the program throughout the study. The participants will receive the exercise equipment for use at home.
RECRUITING
University of Florida Clinical and Translational Research Building, Gainesville
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
University of Florida
OTHER