50
Participants
Start Date
September 3, 2024
Primary Completion Date
March 1, 2026
Study Completion Date
January 1, 2031
Cadonilimab
10 mg/kg (body weight), 60 min, IV. Repeat every 3 weeks for a total of 3 cycles
Paclitaxel-albumin
260 mg/m2 for 30 min. Repeat every 3 weeks for a total of 3 cycles.
Cisplatin
75-80 mg/m2, IV, 1 mg/min. Repeat every 3 weeks for a total of 3 cycles.
Extrafascial hysterectomy
Extrafascial hysterectomy + pelvic lymphadenectomy (or SLN mapping) (For participants who meet ConCerv criteria)
Radical hysterectomy
Radical hysterectomy + pelvic lymphadenectomy ± para-aortic lymphadenectomy (or SLN mapping) (For participants who do not meet ConCerv criteria)
Cone biopsy
Cold knife conization (CKC) (For participants with tumor size ≤2 cm after 3 cycles of chemo-immunotherapy)
RECRUITING
Qilu Hospital of Shandong University, Jinan
RECRUITING
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan
The First Affiliated Hospital of China University of Science and Technology (Anhui Provincial)
OTHER
Women's Hospital School Of Medicine Zhejiang University
OTHER
Southwest Hospital, China
OTHER
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER
Sichuan Cancer Hospital and Research Institute
OTHER
Qilu Hospital of Shandong University
OTHER
Beijing Friendship Hospital
OTHER
Tianjin Medical University
OTHER
West China Second University Hospital
OTHER
Xiangya Hospital of Central South University
OTHER
Gansu Provincial Maternal and Child Health Care Hospital
OTHER
Zhejiang Cancer Hospital
OTHER
Shengjing Hospital
OTHER
Tongji Hospital
OTHER