Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

PHASE2CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

January 1, 2025

Study Completion Date

January 1, 2025

Conditions
Head and Neck Malignant Tumors
Interventions
DRUG

Lactobacillus reuteri Tablets

Lactobacillus reuteri lozenges (NOW Foods, Sweden) contained 2×10\^8 CFU viable cells of Lactobacillus reuteri as the active ingredient.

DRUG

Placebo-containing tablets

Starch preparations that look and taste like Lactobacillus reuteri.

RADIATION

Radiotherapy

One of the inclusion criteria for the study was that patients with squamous carcinoma of the head and neck (including nasopharyngeal carcinoma) needed to receive either radiotherapy alone or simultaneous radiotherapy and chemotherapy.

Trial Locations (1)

610041

West China Hospital, Sichuan University, Chengdu

All Listed Sponsors
lead

West China Hospital

OTHER

NCT06285591 - Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors | Biotech Hunter | Biotech Hunter