Tace With Icaritin in First-line Treatment of Middle and Advanced HCC in Child Grade B Patients

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

December 1, 2024

Study Completion Date

June 1, 2025

Conditions
HCC
Interventions
DRUG

Icaritin

This product is suitable for patients with unresectable hepatocellular carcinoma who are not suitable for or refuse to receive standard treatment and have not received systemic treatment in the past, and the peripheral blood compound markers of patients meet at least two of the following detection indicatorsItem: AFP\>400 ng/mL; TNF-a\<2.5 pg/mL; IFN-y\>7.0 pg/mL.The conditional approval is based on data from an interim analysis of an enriched population in a randomized controlled Phase 11 clinical trial, and full approval for this indication will be subject to confirmation of the clinical benefit of the product in planned confirmatory trials.

All Listed Sponsors
lead

Henan Cancer Hospital

OTHER_GOV