CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

PHASE4RecruitingINTERVENTIONAL
Enrollment

1,200

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

April 1, 2028

Study Completion Date

December 1, 2028

Conditions
ACS - Acute Coronary SyndromeCYP2C19 Polymorphism
Interventions
DRUG

CYP2C19 Genotype Guided DAPT

Patients with \*2 or \*3 carrier will be received ticagrelor 60mg or 45mg bid (if \<50 kg, ≥75 years) + aspirin 100 mg qd; Patients with \*2 or \*3 non-carrier will be received clopidogrel 75mg qd + aspirin 100 mg qd

DRUG

Conventional DAPT

Patients will be conventionally received ticagrelor 90mg bid or clopidogrel 75mg qd + aspirin 100 mg qd

Trial Locations (1)

563003

RECRUITING

Affiliated Hospital of Zunyi Medical University, Zunyi

All Listed Sponsors
lead

Zunyi Medical College

OTHER