382
Participants
Start Date
February 18, 2024
Primary Completion Date
April 30, 2025
Study Completion Date
July 30, 2025
Sivelestat
(1)Experimental group: Received intravenous sivelestat sodium admission to the ICU. Sivelestat sodium was dissolved in 0.9% sodium chloride injection and a one-day dose (4.8mg/kg) was diluted in 50ml of 0.9% sodium chloride injection, which was then sealed for continuous intravenous administration at a rate of 0.2 mg/kg/h for seven consecutive days.
placebo
2)Control group: Receiving the same dose of placebo, 50 ml of saline, were administered intravenously at a rate of 0.2 mg/kg throughout the treatment period without any discernible impact on patient's regular treatment regimen.
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
OTHER