Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

PHASE1CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

March 4, 2024

Primary Completion Date

April 10, 2024

Study Completion Date

April 10, 2024

Conditions
Presbyopia
Interventions
DRUG

LNZ101 (Aceclidine /Brimonidine) ophthalmic solution

Once daily from day 1 to day 8; Everyday, subject will be administered with 1 drop in each eye followed by another drop in each eye 2 minutes later

DRUG

LNZ100 (Aceclidine) ophthalmic solution

Once daily from day 1 to day 8; Everyday, subject will be administered with 1 drop in each eye followed by another drop in each eye 2 minutes later

DRUG

Placebo (Vehicle) ophthalmic solution

Once daily from day 1 to day 8; Everyday, subject will be administered with 1 drop in each eye followed by another drop in each eye 2 minutes later

Trial Locations (1)

200080

Shanghai General Hospital, Shanghai

Sponsors
All Listed Sponsors
collaborator

LENZ Therapeutics, Inc

OTHER

lead

Corxel Pharmaceuticals

INDUSTRY

NCT06270030 - Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia | Biotech Hunter | Biotech Hunter