NCT06269978View on ClinicalTrials.gov

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients with Peritoneal Metastases from Colorectal Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

December 31, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Metastatic Colorectal CarcinomaMetastatic Malignant Neoplasm in the PeritoneumStage IV Colorectal Cancer AJCC V8
Interventions
PROCEDURE

Biopsy

Undergo biopsy

PROCEDURE

Biospecimen Collection

Undergo collection of blood and IP fluid samples

PROCEDURE

Computed Tomography

Undergo CT

PROCEDURE

Diagnostic Laparoscopy

Undergo diagnostic laparoscopy

DRUG

Fluorouracil

Given via IP infusion

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

DRUG

Oxaliplatin

Given via IP infusion

PROCEDURE

Surgical Procedure

Undergo placement of indwelling IP port

Trial Locations (1)

43210

RECRUITING

Ohio State University Comprehensive Cancer Center, Columbus

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Arjun Mittra

OTHER