302
Participants
Start Date
January 15, 2024
Primary Completion Date
February 15, 2026
Study Completion Date
January 15, 2028
Organoid-guided personalized treatment
After the organoid culture is successful, the personalized drug library customized by our team will be used for screening. Sensitive drugs are selected based on the results of drug screening, and the most appropriate personalized treatment plan is selected based on NCCN guideline recommendations, drug safety, and conventional drugs used in the treatment of breast cancer. The personalized drug library customized by our team contains 55 drugs approved by the FDA. For specific usage, dosage and time intervals, please refer to the instructions of the corresponding drug.
Gemcitabine
1000mg/m2,IV, days 1, 8, q3w
Capecitabine
1000mg/m² , PO, bid, days1-14, q3w
Vinorelbine
25mg/m2, IV or 60mg/m² (oral), days 1 and 8, q3w
Eribulin
1.4mg/m², IV, days 1 and 8, q3w
RECRUITING
Yanxia Shi, Guangzhou
Sun Yat-sen University
OTHER