Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 14, 2024

Primary Completion Date

October 5, 2024

Study Completion Date

October 5, 2024

Conditions
Postural Tachycardia SyndromeAutonomic DysfunctionPostural Orthostatic Tachycardia SyndromePOTS - Postural Orthostatic Tachycardia Syndrome
Interventions
DEVICE

GammaCore intervention

Use of the vagal nerve stimulator, GammaCore, on the right side of the neck for two 2 minute stimulations performed 3 times a day

OTHER

STEPS management protocol

STEPS is the acronym for the standard management program for our patients with POTS. It includes liberal use of salt, taking in 90-100 ounces of fluid, gradually increasing the duration of aerobic exercise, possible use of one of two prescription medications (metoprolol, and midodrine), and encouragement to set priority and goals

Trial Locations (2)

55901

Mayo Clinic, Rochester

55905

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT06268288 - Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS) | Biotech Hunter | Biotech Hunter