Study of AZD0754 in Participants With Metastatic Prostate Cancer

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 12, 2024

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Metastatic Prostate Cancer
Interventions
BIOLOGICAL

AZD0754

"Subjects will undergo leukapheresis to isolate peripheral blood mononuclear cells (PBMCs) to produce AZD0754.~During AZD0754 production, subjects may receive bridging therapy for disease control. Upon successful generation of AZD0754 product, subjects will receive treatment with AZD0754 therapy.~Study treatment will include lymphodepleting chemotherapy followed by one dose of AZD0754 administered by intravenous (IV) infusion."

Trial Locations (13)

3002

RECRUITING

Research Site, East Melbourne

10032

NOT_YET_RECRUITING

Research Site, New York

10065

RECRUITING

Research Site, New York

19104

RECRUITING

Research Site, Philadelphia

30322

RECRUITING

Research Site, Atlanta

33612

RECRUITING

Research Site, Tampa

63110

RECRUITING

Research Site, St Louis

66205

NOT_YET_RECRUITING

Research Site, Westwood

77030

RECRUITING

Research Site, Houston

91010

RECRUITING

Research Site, Duarte

WITHDRAWN

Research Site, Duarte

02215

NOT_YET_RECRUITING

Research Site, Boston

07601

RECRUITING

Research Site, Hackensack

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY